The history of patenting life

A major philosophical issue that many people have with biotechnology is patents on genes or whole organisms. It seems obvious that a plant, animal, or even bacterium is very different than a new piece of exercise equipment or anything else that might get patented. Should a breeder or geneticist be allowed to profit from his or her work? When thinking about complex subjects like this, it can help to get a little perspective by

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More is better – when it comes to IP?

One of the best parts of the Maize Genetics Meeting is the opportunity to have discussions with scientists working in a variety of fields from academia, industry, and NGOs. Conversation this afternoon veered towards intellectual property (IP) and biotechnology for a bit. It’s a contentious subject for a lot of reasons, but some new ideas I’d never thought of before came up today. I don’t have a background in IP, so please feel free share your thoughts and ideas in the comments!

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BIO-FABulous!

Genetic Engineering & Biotechnology News reports that UC Berkeley and Stanford University are collaborating on a project to build a biotechnology resource called BIOFAB. This stands for International Open Facility Advancing Biotechnology. (IOFAB?) I guess the missing B stands for BYOB, or “Bring Your Own B.” What’s so fabulous about BIOFAB?

Well, genetic engineering requires all sorts of tools. There are the various parts of genes that you need, from the promoter sequence, to the terminator sequence, enhancers, repressors, not to mention the functional part of the gene itself. But then you also need the tools to get it into your target organism… and the list goes on. It takes time, research, and least of all piles of $$$ to get all these parts together to make it all work. It’s no small wonder that the only companies to successfully launch GE crops are the big ones.

But there’s a new field emerging that is much more demanding than splicing a few genes together – synthetic biology. Building new organisms means that an organismal toolkit will have to be put together. Preferably one that many people can use, free of patent restrictions that could hinder their use by academic labs and small startups. Something open-source…

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Terminator 2: My Mission is to Protect You

In discussions about GE crops, one of the contentious topics that often comes up is the use of what has been effectively dubbed “Terminator” technology. These are crops that are engineered to produce sterile seeds that cannot be regrown. The use of this technology to force farmers to repurchase their seeds every year is often what causes the greatest objection from opponents of genetic engineering. But what is interesting is that like the films where this technology gets its nickname, it can also be used to protect seed-saving farmers.

“Terminator” technology, also referred to as “Suicide Seeds,” are marketing terms coined by GE opponents to reframe what is technically called Genetic Use Restriction Technology, or GURT. This technology can take several forms, the most widely discussed one was developed by scientists working at the USDA and the Delta and Land Pine company, which is now owned by Monsanto. It works by means of three engineered genes, that when brought together in one plant, they act in combination to halt the development of embryos in the seeds the plant produces. The result is a plant that produces food as normal, but does not produce fertile seeds.

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Is opposition to GE crops in Europe a Scientific Flip-Flop?

Just out today, Seed Magazine has assembled a “Scientific Flip Flop” about Genetically Engineered crops. The article begins with an introduction into the curious case of European nations who embrace scientific conclusions in other areas of science, but not in this area.

Most Europeans don’t consider themselves to be anti-science or particularly technophobic. In fact, Europe’s full embrace of the scientific consensus on another environmental issue, global warming, has enabled the continent to take the clear lead on climate change, with the most ambitious emissions targets, the first carbon trading market, and the greenest urban infrastructure plans on the planet.

Europe’s scientific disconnect is more broadly true of eco-minded citizens worldwide: They laud the likes of James Hansen and Rajendra Pachauri but shrink in horror at the scientist who offers up a Bt corn plant (even though numerous studies indicate that Bt crops—by dramatically curbing pesticide use—conserve biodiversity on farms and reduce chemical-related sickness among farmers).

So why the disconnect? Why do many environmentalists trust science when it comes to climate change but not when it comes to genetic engineering? Is the fear really about the technology itself or is it a mistrust of big agribusiness?

Contributing their views (in order) are Pam Ronald, Raj Patel, Nina Fedoroff, and Noel Kingsbury. Read the article, I’ll offer a few opinions about it after the jump.

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